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Given that p300 and CBP interact with and mediate the activation of other transcriptional regulation factors it is clear that these proteins are regulators of multiple signal transduction pathways in addition to their roles in steroid/thyroid hormone receptor functions

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1122 The NNT for ALA is 2.7, which is comparable if not lower than most of the traditional first-line agents (Table 1)

Chemical peel (TCA or glycolic) Chemical peels such as TCA or glycolic acid peels are sometimes used to improve the appearance of very superficial pigmentation