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case reports document serious systemic toxicity and rhabdomyolysis at mega-doses (6 mg) [4]
The combination of drugs was well tolerated with no significantly increased side-effects over either sildenafil or PT-141 alone
[PMC free article: PMC507492] [PubMed: 8698874] 360
The BDA recommends consuming at least 1.5 to 2 liters of water daily when taking water-soluble vitamins

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