glutathione and thioredoxin antioxidant pathways Frontiers Interconnection of glutaredoxin, peroxiredoxin, thioredoxin,

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118,119,120,121 In addition, it has been observed that naive T cells from older individuals exhibit reduced responsiveness to the superantigen toxic shock syndrome toxin-1 compared to younger individuals, 122,123 which may be caused by low dual specificity phosphatase 6 levels in naive T cells, resulting in a rise in the threshold of TCR activation