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Post-seizure samples revealed alterations in seven metabolites, including hippurate, pyroglutamate, isovalerate, creatinine, threonine, 3-methyl-2-oxovalerate, and 2-oxoisocaproate
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This work develops the first mathematical model for the GSH antioxidant system in the outer retina, capturing the most essential components for formation of ROS, GSH production, its oxidation in detoxifying ROS, and subsequent reduction by NADPH
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