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To overcome challenges such as biosafety, off-target effects, and clinical translatability, strategies successfully explored in other diseases, such as biodegradable or organicinorganic hybrid nanozymes, pH-responsive targeting designs, erythrocyte membrane coatings, and ROS-responsive carriers, may be adapted to enhance tissue specificity and safety in IMID treatment

For musculoskeletal use, it is commonly considered for tendon irritation, ligament sprains, muscle strains, fascia-related pain, overuse injuries, and joint-adjacent soft-tissue pain

Increased power levels have been shown to result in the production of volatile carbonyl species (48, 51, 117) and increase the mass of aerosol produced (51, 117)

Wang X, Yu P, Liu X, Jiang J, Liu D, Xue G

The prevalence of thyroid nodules with a diameter of more than 0.5 cm in Chinese adults is as high as 20.43% (15)