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elegans , research into the dynamic roles of this enzyme superfamily in detoxification and signalling will further our understanding on how the redox environment is mediated by enzymatically-controlled GSH-dependent redox processes

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When cells are exposed to increased levels of oxidative stress, GSSG accumulates and the ratio of GSH/GSSG decreases to ratios as low as 10:1 and even 1:1

Bilirubin also effectively reversed the doxorubicin-induced bradycardia, QT prolongation and arrhythmia in mice (Figures 2GK)

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