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While a previous study indicated that plasma GSH concentration was highly correlated with the intrahepatic level [13], whether the expression of GSH and its dependent antioxidant enzyme activities in plasma are correlated with their expression in tissues during the development of HCC is unknown

All animals used in the experiments were kept in positive-pressure air-conditioned units (25C, 50% relative humidity, 12-h light/dark cycle)

Maturation markers CD40, CD80 and CD86 were also significantly reduced