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The NIH Vitamin B12 Fact Sheet for Health Professionals notes that oral supplementation is appropriate for many patients who do not have intrinsic factor deficiency

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2 Vitamin B12induced acne can be differentiated from acne vulgaris by the presence of pruritus, correlation between drug use and eruption, sudden onset, patient age, and the absence of comedones and microcysts

Side effects are rare and typically limited to mild injection-site tenderness