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Any new, changing, asymmetrical or irregular pigmented lip lesion warrants assessment with dermoscopy and often biopsy before any cosmetic treatment Treatment confirmed labial melanotic macules can be left alone or treated cosmetically with laser ablation or excision biopsy if cosmetically prominent Other benign lesions Fibroma firm fibrous nodule on the inner lip, usually from chronic minor friction trauma

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Emergence of a high-plasticity cell state during lung cancer evolution

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Curr Pulmonol Rep