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The power to detect differences between the study groups is larger than what is projected here as we will measure most of the outcomes more than once and also use these repeated measurements in the same analyses, adjusting for interdependence within a child using mixed effects models, generalised estimating equations or other appropriate methods

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It represents an actual or potential health risk to the athletes 3

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doi:10.1073/pnas.050909910

This is a non-negotiable clinical and legal requirement not a formality