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Redox-responsive fluorescent probes with different design strategies

Glutathione is often discussed in oxidative stress research because it is associated with antioxidant response systems and reactive oxygen species regulation

For example, in Escherichia coli O157:H7 (Figure 6A), the interactions between -PL and phospholipid groups result in distorting and shriveling of the cell membrane in a non-specific, carpet-like mechanism, in which the membrane is forced to fold in on itself, contributing to vesicle/micelle and toroidal pore formation (Hyldgaard et al., 2014)

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