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Once inside the mitochondria, the fatty acids undergo -oxidation, which breaks them down into acetyl-CoA molecules
In neonatal onset CACT, there is a metabolic crisis that often results in death from cardiopulmonary complications and/or liver failure
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doi: 10.1038/nri3623 123 BanoAChakerLMukaTMattace-RasoFUBallyLFrancoOHet al
10.1038/s41387-020-00142-z 76
