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A lack of vitamin B12 can result in symptoms like pale or jaundiced skin and weak, brittle nails

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Doses above ~500 mcg/day are not generally linked to added benefit in the reference literature, and none of this reflects proven human efficacy

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Metformin and Vitamin B12 Metformin is prescribed to people with type 2 diabetes to help manage their blood sugar levels

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Available online: 34.Rizzol G., Lagan A.S

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Clinical trial data with orforglipron have shown no signal for thyroid C-cell pathology or MTC

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