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Second, a reduction in tubular reabsorption of both free carnitine and acylcarnitine has been reported during VPA treatment [45,46], Third, VPA reduces endogenous synthesis of carnitine by blockade of the enzyme butyrobetaine hydroxylase

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Krall AS, Mullen PJ, Surjono F, Momcilovic M, Schmid EW, Halbrook CJ

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This compound can affect the pharmacokinetic profiles of other orally administered drugs at various stages, that is: absorption, distribution, metabolism, and elimination

Nuclear status of immature and mature stallion spermatozoa