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A 2025 study in Aging Cell confirmed these findings in both normal epithelial and fibroblast cell lines, identifying hTERT upregulation as the primary mechanism in normal cells (4)

Liu X, Zeng L, Liu J, Huang Y, Yao H, Zhong J, et al

Polletta L, Vernucci E, Carnevale I, Arcangeli T, Rotili D, Palmerio S, Steegborn C, Nowak T, Schutkowski M, Pellegrini L, Sansone L, Villanova L, Runci A, Pucci B, Morgante E, Fini M, Mai A, Russo MA, Tafani M

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6.3 Dehydroascorbate reductase (DHAR) The expression of DHAR has been upregulated by several types of stress in plants, which imparts tolerance mechanisms to affected plant spp

Exploring liraglutides mechanism in reducing renal fibrosis: the fsp1-coq10-nad(p)h pathway