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BAP1 suppresses the expression of SLC7A11 to inhibit cystine uptake, leading to lipid peroxidation and ferroptosis

PloS One (2011) 6(7):e21800

2015 Mar;125(3):926-38

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We also evaluated nuclear factor erythroid 2-related factor 2 (Nrf2), a transcriptional factor of genes involved in antioxidant activity 15 and regulator of oxidative stress that is activated by AMPK 16,17
