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NAPstar3b was found to have a slightly decreased K d(NADPH) but an approximately 3-fold higher K d(NADH) (Fig

The compound is stable at pH 5.5-7.0 and should not be mixed with chelating agents (EDTA) that would strip the copper ion

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In fact, mutagenesis of these residues abolishes CD38 NADase activity and increases its cyclase activity [60]

doi: 10.1161/01.RES.0000232546.92777.05 112 MacaulayN.ZeuthenT