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Supplementary information The online version contains supplementary material available at 10.1038/s41556-023-01136-6

Injection areas at month 12 maintained the original fat lobule structure, without any abnormal collagen tissue deposition or fibrotic nodules

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In Vivo Dissolution Calculator Please enter the basic information of animal experiments: Recommended: Prepare an additional quantity of animals to account for potential losses during experiments

This research was supported by the DZNE institutional budget