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Briefly, to generate MIA mice, pregnant C57BL/6J mice received a daily 30 g/kg intraperitoneal injection of recombinant IL-6 (R&D Systems, Minneapolis, MN) during E12 50
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Macrophages deficient in cholesterol efflux transporter ATP-binding cassette transporter A1 (ABCA1) have enlarged lipid rafts and exhibit hyper-responsive to LPS 51
The present review highlights the OS hypothesis of AD, including amyloid beta-peptide-associated mechanisms, the role of lipid and protein oxidation unraveled by redox proteomics, and the antioxidant strategies that have been investigated to modulate the progression of AD

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