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is supported by the Portuguese Fundao para a Cincia e Tecnologia (FCT) (grant number SFRH/BPD/77448/2011, part of the EDCTP2 program supported by the European Union)

Knockdown of SREBP in CRC cell lines significantly reduces intracellular fatty acids, cholesterol, and triglycerides, inhibiting tumor cell proliferation

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Yet more complex are the regulation and modulation of expression as well as activity of CWHs

[DOI] [PubMed] [Google Scholar] 5.Dibenedetti DB, Nguyen D, Zografos L, Ziemiecki R, Zhou X