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[7] Klicek, R., Sever, M., Radic, B., & Sikiric, P

When used outside of a medical setting, dissociative drugs can cause several adverse side effects, including hallucinations and the distortion of colors, sights, and sounds

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In aged mice, research has demonstrated several key changes that contribute to the development of DE, including disruption of corneal barrier function, heightened ocular surface inflammation [151], loss of meibomian glands [152], and increased levels of oxidative stress within the lacrimal glands [153, 154]