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doi: 10.1111/liv.15930 89

This concentration range is three orders of magnitude higher than normal extracellular levels because the GSH concentration in circulation has known to be M range

Stein AD The Impact of Nutritional Interventions beyond the First 2 Years of Life on Linear Growth: A Systematic Review and Meta-Analysis

Once oxidized, glutathione can be reduced back by glutathione reductase, using NADPH as an electron donor

Extracellular GSH is selectively transported into the cell but somer of tissues requiring degradation to single amino acids before transport into the cell

Subsequently, GSH acts as an electron donor for glutathione peroxidase (Gpx) to reduce H 2 O 2 to H 2 O, i = 1 = 1 \)