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& Hamid, R
PMID: 16029815
Most importantly, unlike most other therapeutic agents currently in trial which offer prophylactics, ADAC can be both otoprotective and therapeutic
The results of in vitro experiment suggested that TS demonstrates both protective and restorative effects in relation to sensorineural hearing loss by regulating several genes related to hearing loss, including Transient Receptor Potential Vanilloid 1 (TRPV1) channel, T-type calcium channel (Cacna1h), and nerve growth factor (Ngf)
Direct blockade of mTOR with sirolimus also exerts promising clinical efficacy and moderated mitochondrial oxidative stress in patients [23] and mice with SLE [24,25]
Similar limitations are common in the application of FMT in anticancer treatment
