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[DOI] [PubMed] [Google Scholar] 9.Sikiric P., Drmic D., Sever M., Klicek R., Blagaic A.B., Tvrdeic A., Kralj T., Kovac K.K., Vukojevic J., Siroglavic M., et al

IDO activation can reduce tryptophan and increase toxic metabolites of the kynurenine pathway, which increases glial activation, neuroinflammation, toxicity, and neuronal death