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Aqueous solvents such as sterile water or bacteriostatic water are preferred for in vivo rodent studies because they eliminate the confounding variable of DMSO's own biological activity, which includes membrane permeabilization and anti-inflammatory effects

The rats were euthanized, and tissue samples (brain, heart, kidneys, liver, spleen, lung, stomach, intestine, muscle, grease, ovaries, womb, testicles, and thymus) were collected at 3 min, 10 min, 1 h, and 24 h after administration (three males and three females at each time point)

Stability is maintained refrigerated at 28C post-reconstitution, with usage recommended within 60 days

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Many of the medications and injections marketed to alleviate joint-related pain also have many negative side effects, even causing the joint to deteriorate over time
