the klow Discover the KLOW Bundle: Peptronic

Ruan et al., 2023)

Interestingly, the excessive uptake of neuronal -synuclein by astrocytes can lead to accumulation of aggregates of this protein in astrocytes, and cause an upregulation of IL-1 , IL-1 and IL-6, followed by the release of TNF- and IL-6 [6]

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Igarashi M

C., Chen Y., Zheng M., et al

c-MET inhibition using savolitinib significantly suppressed sphere formation by the patient-derived CRC cells with low ABHD5 and high MET expression, indicating that inhibiting c-MET is an effective strategy for eradicating the CRC stem cell compartment, characterized as low ABHD5 and high c-MET expression (Gu et al., 2021)