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Cell Chem Biol 27(4):365375
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The group of Von Zastrow was the first to identify a protein, named GASP for GPCR associated sorting protein, which could actively target DOR to lysosome (Whistler et al., 2002)
doi: 10.4084/mjhid.2013.070 5 HaqueMFBoonhokRPrammanananTChaiprasertAUtaisincharoenPSattabongkotJet al
The end products of purine metabolism, uric acid, a potent antioxidant, have been reported to be found in decreased levels in MDD 71,72,73 , while lower cerebro-spinal fluid (CSF) levels of hypoxanthine and xanthine, the two metabolites preceding uric acid, have previously been linked with depression 74
