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Meanwhile, 25-OHC markedly upregulated cytochrome b5 reductase 1 (CYB5R1) and POR, suppressed GSH expression, and promoted lipid peroxidation, thereby enhancing the sensitivity of IMS32 cells to ferroptosis and aggravating neuroglial injury

10.1016/j.abb.2004.02.008 Arch

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This product and its associated data have not been evaluated by the U.S

However, the loss of Txnip in LSEC leads to sinusoidal capillarization, downregulated NO production, and increased release of proinflammatory cytokines and adhesion molecules, and aggravates alcohol-induced liver damage, inflammation, and fibrosis (Jung et al., 2024)

Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism