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10.1113/jphysiol.1992.sp019104 J

PMID: 40371136 CarcinogenesisSIAH1/CTR9 axis promotes the epithelial-mesenchymal transition of hepatocellular carcinoma

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The proposed mechanisms by which PEITC enhances the effects of other agents or drugs are: reduction in the availability of GSH for conjugation leading to efflux and inactivation, inhibition of drug transporter proteins like MRP and PgP, hence improving drug availability to the cells and induction of pro-apoptotic pathways to counteract anti-apoptotic mechanisms