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In a study looking at chronic stress, Magnolia administration restored circadian cortisol patterns and improved REM sleep architecture, indicating a capacity to rebalance HPA and SCN outputs

5.3 Potential mechanisms of dietary fiber affecting depression (1) Mood regulation mediated by SCFAs produced via gut microbiota fermentation Dietary fiber cannot be digested and absorbed by the human body but can be partially or fully fermented by gut microbiota (122)

It increases serotonin levels in the brain to improve mood and can also be used offlabel for OCD, panic disorder, and PTSD

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doi: 10.1038/s41592-020-00981-9 [DOI] [PMC free article] [PubMed] [Google Scholar] Associated Data This section collects any data citations, data availability statements, or supplementary materials included in this article