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The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes

Well explore the mechanisms behind emerging therapies, review recent clinical trial outcomes, and discuss how these innovations could soon redefine the standard of care

Rajanahally S, Raheem O, Rogers M, et al
One animal study (Valdecantos et al., ADA 2024) showed obese rats given both compounds at sub-maximal doses lost more weight than either compound alone

Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney

Researchers derived it from a partial sequence of the naturally occurring Body Protection Compound (BPC) found in gastric juices
