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Alpha Lipoic Acid

SARS-CoV-2-infected patients with COVID-19 disease show alterations in the glucoseinsulin axis leading to hyperglycemia, hyperinsulinemia and insulin resistance, increased oxidative/nitrosative stress, and significantly decreased vitamin D, thiols, total-antioxidant-capacity, GSH and selenium (Soto et al., 2022)

Rongsong Li at UCLA

They discovered that circ-0000231 acts through the circ-0000231/miR-140/RAP1B axis, leading to increased expression of E-cadherin in paclitaxel-resistant tumor cells

GSEA analysis revealed significant enrichment of IFN-I signaling pathways in the Lig group (Fig S6a), while the corresponding heatmap analysis confirmed upregulation of IFN-Iresponsive genes in Lig-derived neutrophils (Fig S6b)