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In AML, Liu et al

Astragalus Membranaceus: A Review of its Protection against Inflammation and Gastrointestinal Cancers
Mediation by nf-kappa b of cytokine induced expression of intercellular adhesion molecule 1 (icam-1) in an intestinal epithelial cell line, a process blocked by proteasome inhibitors

doi: 10.1002/mnfr.200900277

Franklin, C

Freeze-thaw cycling is especially destructive to peptides each cycle forms ice crystals that physically shear the molecule, so even one accidental freeze can tank a vial
