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Common antioxidants include: enzymes such as SOD, CAT and glutathione related enzymes (GPx, GR, GST and thioredoxin reductase) and heme oxygenase [66], non-enzymes such as vitamins (A, C, E) and carotenoids, flavonoids, glutathione and other antioxidants minerals (copper, ferritin, zinc, manganese, selenium etc.) [67, 68]

Dysfunction of astrocytes and regulatory pathways, including proteins, ion channels, and protein synthesis, may lead to the development of neurological diseases (Pekny et al., 2016

How Glutathione Supports Renal Function Rather than causing damage, glutathione is often studied for its ability to protect the kidneys from various stressors

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Keywords Inflammation, Insulin resistance, Lipid metabolism, Leptin, Metabolic dysfunction-associated fatty liver disease, MAFLD Introduction Metabolic dysfunction-associated fatty liver disease (MAFLD), the recently proposed term replacing nonalcoholic fatty liver disease according to a multi-society Delphi consensus statement, has emerged as the most common chronic liver disease, 1,2 affecting over 25% of the general adult population and more than 50% of individuals with type 2 diabetes mellitus (T2DM)

Part I: heterocyclic modifications of the core structure