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Exhausted T-cells lose their ability to effectively clear pathogens and instead contribute to a smoldering state of systemic inflammation, releasing high levels of pro-inflammatory cytokines such as Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-)

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Polet, M

W., Malinow R
These discrepancies for the role of NO in cell death might be due to the differences in plant species, redox state, and growth conditions

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