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B12 is primarily present in animal products

Sucharita S, Dwarkanath P, Thomas T, et al

Patients and healthcare professionals alike recognise that significant caloric restriction can lead to micronutrient deficiencies if dietary quality is not maintained

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4.11 Total proteomics and phosphoproteomics analysis by liquid chromatography combined with tandem mass spectrometry Be(2)-C cells were cultured in triplicates in 10 cm dishes and treated the following day either with MitoQ IC50, DPI IC50, Vin IC50, (M+D)/2, (M+D+V)/3, or vehicle for 24 h and washed once with PBS

Low B12 can cause issues with anaemia, fatigue, and lack of focus