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Moreover, ascorbic acid is essential for collagen biosynthesis in fibroblasts [70]

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Mice with signs of unrelated illness, abnormal baseline renal function, or technical failure during surgery/crystal injection were excluded from analysis

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As seen with probably all NOX enzymes, there are spatially distinct mechanisms of receptor-mediated NOX1 activation and generation of ROS, confirming that compartmentalisation is necessary for integration of redox-dependent signaling

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Sun R, Wang Y, He H, Wan Y, Li L, Sha J, et al

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Glutathione synthesis involves two closely linked, enzymatically controlled reactions that utilize ATP

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