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Sirt7-deficient HSCs exited quiescence and exhibited an ageing phenotype, including the increase of PFSmt, apoptosis, a decrease of reproductivity, and biased bone marrow differentiation

Finally, no observed differences were seen between the two groups (20)

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Innovations such as nanoparticle carriers, liposomes, cyclodextrin complexes, and mucosal delivery methods show promise in preclinical studies

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Journal of neural transmission