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The thioredoxin superfamily: redundancy, specificity, and gray-area genomics

Of note, Ser/Cys-94 makes contacts with a sulfate ion in the IdeS crystal structure (Wenig et al, 2004) and a partially disordered 2-mercaptoethanol molecule in the gasMac-1 crystal structure (Agniswamy et al, 2006)

Resistance to anti-IGF therapies is mediated by other receptor tyrosine kinases and their downstream targets through complex interactions

While some studies indicate an increase in the DNA-binding activity of NF-kB under low-Zn conditions, others suggest that the nuclear translocation of active NF-kB is compromised by Zn deficiency, leading to a downregulation of NF-kB targets and inhibition of proliferation and survival pathways [21,51]

Facchinetti, F., Cavalli, P., Copp, A

Shinzhen, 2006)