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In vivo, oral ALC supplementation restored social preference and medial prefrontal cortex MBP expression in PWSI mice, whereas cuprizone co-administration abolished these effects, suggesting that the therapeutic effects of ALC are closely associated with its impact on myelination

Mishra A, Reddy IJ, Gupta PS, Mondal S

This study was supported by National Institute on Aging grant AG023265-01 (B.N.A and J.L), Natural Sciences grant from the Shanghai Science and Technical Committee 04DZ14007 (J.L) and the Chinese Academy of Sciences 05PG14104 (J.L.)

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Nevertheless, hazardous alcohol drinking levels are often associated with reduced fat mass, body weight, and BMI [120123], and clinical observations ( e.g

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