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A subcutaneously administered investigational RNAi therapeutic (ALN-CC5) targeting complement C5 for treatment of PNH and complement-mediated diseases: preliminary phase 1/2 study results in patients with PNH
10.1073/pnas.1102999108 143

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Cryopreservation in 95% serum with 5% DMSO maintains colony formation and chondrogenic abilities in human synovial mesenchymal stem cells
Deane et al
3) sirtuins, main sensors for nutrient state, are activated by increased NAD + /NADH ratio 12