zinc supplementation increased glutathione synthase ncbi Frontiers Zinc and Diabetes: A Connection

894 Acid sphingomyelinase (ASM)-mediated autophagy activation is critical for hyperglycemia -induced GPX4 degradation, and inhibition of ASM improves osteogenic function by reducing hyperglycemia-induced GPX4 degradation and subsequent ferroptosis

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20 BerthillerF.CrewsC.DallAstaC.SaegerS.De, HaesaertG.et al (2013)

It has been demonstrated that FFA-treated hepatocytes show an increase in the expression of pro-apoptotic proteins and apoptosis regulators upregulated by tumor suppressor genes, a process that is accompanied by a decrease in the expression of the anti-apoptotic protein B-cell lymphoma-2

After nuclear translocation, the phosphorylated form of STAT3 acts as a transcriptional factor that boosts the production of genes related to inflammation (Huang et al

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