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in turn, chronic sleep disturbance is correlated with increased risks of a range of health problems, including cardiovascular, metabolic, neurologic, and psychiatric conditions, as well as frailty and mortality

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In the presence of oxygen and transition metal ions, H 2 O 2 can produce OH via the Fenton reaction, as described by Halliwell and Gutteridge (1989, 2015)

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Ischaemia and reperfusion injury of rat liver increases expression of glutathione S-transferase A1/A2 in zone 3 of the hepatic lobule