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However, consistency matters more than timing
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doi:10.18433/J3PK7P
As shown in Table 1 and Figure 6, the small molecule inhibitors targeting NNMT can be categorized into SAM-competitive inhibitors, NAM-competitive inhibitors, Dual-substrate-competitive inhibitors and isomerization inhibitors
The mechanisms differ entirely
A common reason for incomplete improvement is that treatment focuses only on suppressing nerve pain, without identifying what is maintaining that sensitivity over time
