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Deficiency of lymphotoxin-alpha does not exacerbate high-fat diet-induced obesity but does enhance inflammation in mice Am J Physiol Endocrinol Metab 302 8: E961-71

Sources of cells that contribute to atherosclerotic intimal calcification: an in vivo genetic fate mapping study Cardiovasc Res 94 3: 545-54

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Mitochondrial dysfunction not only impairs fat homeostasis in the liver but also leads to an overproduction of oxidative stress-inducing reactive oxygen species (ROS) that trigger lipid peroxidation, cytokine overproduction, and cell death

Some of that fuel goes towards maintaining the systems themselves charging the batteries, cycling coolant and oil through the engine, etc