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Cytosolic GSH can be enzymatically degraded into the cell [20,21], so that Glu, Cys, and Gly can be reused for the synthesis of new GSH (Figure 2B) [21]

pGSK: phosphorylated glycogen synthase kinase 3

Assume that the observed standardized incidence ratio (SIR) is 2, but the prevalence of smoking in the cohort was not taken into account in its calculation, so that confounding could explain the observed effect

But health should always come before trends

This is not uncommon and may be related to the body adjusting to a rapid increase in B12 availability, especially in patients who were significantly deficient

PMID 6179438