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NEIL3 is perhaps the most intriguing of the three due, (i) to its large structure that includes an extended C-terminal domain containing additional zinc finger motifs, (ii) the replacement of the usual proline residue as the nucleophile with valine, and (iii) its restricted expression pattern in mammalian cells (Liu et al., 2013)

doi: 10.1385/1-59259-922-2:163

In fact, one 2023 study noted that "NAC's primary role is to replenish glutathione stores." Remember, glutathione is composed of three amino acids

In the case of Siglec-8, its known ligand from human studies contains Neu5Ac (the 6-sulfo-sialyl Lewis X has Neu5Ac) (197)

that contains several chemical compounds, including caffeic acid, p-coumaric acid, cinnamic acid, aromadendrin, isosakuranetin, and artepillin C, was previously reported as the main source of green propolis with potent antioxidant activity that prevents against oxidative mitochondrial damage (Guimaraes et al., 2012)

The expression of the proteins E2F1, Cyclin E, CDK2 and MCM7, which characterize the progression in late G1 phase and the commitment to DNA replication, was also postponed in Gstp1/2 / (Figure 5c)