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CRISPR/Cas9 mediated KO LentiCRISPR v2-sgNTC (non-target control), sgFSP1 (FSP1 knockout), sgDHODH-2, sgDHODH-4 (DHODH knockouts) were a gift from Boyi Gan (Addgene plasmid #125836

Analgesic, antipyretic, anti-inflammatory, antimicrobial, anti-diabetic, anti-cancer, analgesic, and diuretic are some of the many traditional medicinal uses of LS 15

Vitamin E deficiency due to increased consumption in beta-thalassemia and in Gauchers disease

Yes, it can be for individuals with severe kidney dysfunction, hypocalcemia, or pregnancy

It helps the brain repair itself, reduces fatigue, boosts alertness, and improves cognitive performance

The superimposition of these two effects enhances the anti-apoptotic effect and reduces the dosage requirement of a single component, providing a potential solution for adjuvant therapy to cisplatin chemotherapy, reducing side effects and improving the quality of life of patients (Primadewi et al., 2023)