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Nitrosative stress is also present, as illustrated by markers of nitrosative stress such as increased NOS and NO (182, 297), peroxynitrite (182, 297), elevated NF- production (182), and nitrate after exercise (182, 297)

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Furthermore, a diet based on an increased intake of carbohydrates and fats leads to increased production of free radicals, directly affecting mitochondrial metabolism

Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function