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10.1007/s00508-015-0742-6 140 MillerA.ShapiroS.GershteinR.KinartyA.RawashdehH.HonigmanS.et al

The novel triterpenoid CDDOme potently synergizes with inhibition of bcl-2 function to induce apoptosis in AML via disruption of intracellular redox domeostasis

Furthermore, its ability to modulate the PTEN/AKT pathway and enhance the efficacy of chemotherapy drugs such as sorafenib underscores its potential in combination therapies
As we grow older or face sun and pollution, our glutathione stores drop

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Zhan Y, Zhang Z, Yin A, Su X, Tang N, Chen Y, et al